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Learner Reviews & Feedback for Epigenetic Control of Gene Expression by The University of Melbourne

4.8
stars
791 ratings

About the Course

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Top reviews

NN

Aug 1, 2021

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

MM

Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

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51 - 75 of 215 Reviews for Epigenetic Control of Gene Expression

By EDUARDO R P

Sep 28, 2019

It is a somewhat complicated course even knowing a little about the subject, however it was an excellent course and I learned a lot. I discovered new topics and acquired new knowledge. Congratulations!

Thank you for sharing this course.

By Antonina K

Mar 26, 2016

As far as we have no Genetic, no Epigenetic courses in our medical universities. I feel that I have a huge gap in my knowledge in this field. I am so happy that I can attend such interesting and necessary course. Thank you very much)

By Claudia B

Mar 30, 2016

What can I say? An extremely complete course, very resourceful, dynamic and with great quality content from reliable sources. If you are interested in genetics, you will love this take on epigenetics; definitely worth it.

By Vinicios A

Aug 13, 2017

This course is an incredible introduction to the Science of Epigenetics. Thanks to the course I've learnt a lot about Epigenetic and now I feel confident to read and understand all the papers in this field of knowledge.

By salbiha 5

Jul 23, 2023

It is the best opportunity for students like me who want to pursue a career in research for cancer. It helped me a lot and provide me with a lot of information about Epigenetic Modifications In the context of Cancer

By Hugo F

Oct 16, 2017

Really good course! The design of the last assignment is more close to what I believe online courses should do. It really challenges yourself to apply the knowledge acquired from lectures and reading material.

By Paul S

Mar 30, 2019

Well organized and thought out. Developed the concepts well with clear examples from literature. Gave an understanding of the state of the field and where there are things that still need to be worked out.

By Vanessa L

Mar 9, 2017

I really enjoyed this course it's really interesting and I learned a lot about epigenetics. I really liked the professor and the way she explained and really enjoyed the materials she suggested us to read.

By Sydney G

Jan 23, 2023

Very informative, especially if you already have a background in genetics/molecular biology. I would recommend this to anyone who is thoroughly interested in the subject, as it covers a lot of material.

By Mary M

Oct 2, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

By BARAIYA D H 1

Apr 25, 2020

It was very informative course and will help me in my future studies.In between week 3 was bit tough to understand and keep all things in mind. But overall course was amazing. Thank you.

By Aditya A D

May 13, 2020

Amazingly structured and delivered course by the entire team. Including a few practical assays or how to read some of the assay results related to epigenetic techniques would be welcome.

By Boris M

Aug 14, 2017

One of the best organized and implemented courses I have taken so far. For someone who had barely any experience with epigenetics, I feel this gave me a proper introduction to the field.

By HanuRam

Dec 18, 2016

A quintessential course for Genetics students all over the world. Very nicely prepared and elucidated by Dr. Marnie Blewitt .

Many many thanks to Dr. Marnie Blewitt & Coursera team.

By Thomas W

Aug 24, 2017

Very informative! Before starting this course I didn't even know epigenetics was a word. Now I feel I have a very good grasp of the basics of one of the core concepts of genetics.

By Dominika B

Sep 28, 2016

This was an AWESOME course. Really exciting, interesting, AND surprising, I never thought there's that much to talk about in epigenetics! I'm going to recommend it, definitely :)

By Vinícius

Nov 24, 2020

Excellent course! The topic isn't an easy one, but Dr Marnie Blewitt was brilliant and her explanation is clear and very good. Besides that, this course provides good support.

By Vasisht V S

Aug 8, 2018

A very informative course which starts from the basics and goes up all the way and the pace of the course is also perfectly set for anyone from professionals to first-timers.

By Ziwen L

Dec 12, 2016

Well constructed course and carefully designed questions. It is very useful for someone with biological and/or biomedical background to expand their knowledge on epigenetics!

By Alagbe O A

Nov 27, 2019

The lectures were enlightening and easy to follow and understand. there were also a lot of examples that made the lectures easy to understand. I totally loved and enjoyed it

By Lusya M

Jun 19, 2016

The course is very interesting for those who like Genetics. The lectures are delivered in an understandable manner, and the motion pictures make everything clear right away.

By Arthur V L

Dec 11, 2016

Excellent course by an expert in the field. Full appreciation requires a background in biochemistry and genetics, but still a lot can be learned by anyone with interest.

By Hina K

Nov 17, 2018

This course is well taught and some important concepts are repeated over and over again during the course so the concept lingers in the brain as if it was there already.

By Andrew E M

Dec 13, 2016

A great course! I certainly learnt a lot. Please note, that if you haven't studied a scientific course before, then I think you would find this course too challenging.

By Václav B

Oct 25, 2017

This course was really inspiring and I really enjoyed the part about histone modification, X chromosome inactivation and the influence of an environment on epigenome.